Utilizing Helix’s proprietary Next Generation Sequencing (NGS) technology and uniquely personalized suite of DNA-powered products, research teams at Renown Health and the Desert Research Institute (DRI) plan to offer an additional 40,000 Nevadans the opportunity to have their DNA sequenced and participate in phase two of the study. The Healthy Nevada Project will offer study participants a DNA kit from Helix that provides information on personal traits or ancestry, and a Helix.com account which will enable them to explore additional DNA-powered products through the Helix App store if they choose.
In September 2016, the pilot phase of the study enrolled 10,000 participants in less than 48 hours and completed DNA sample collection in just 60 working days. Participants ranged from 18-90 years old from 135 zip codes in northern Nevada. Socioeconomic survey information was also collected using an advanced, confidential online survey tool. Research teams are currently working on the first peer-reviewed scientific results from the study after gaining valuable community and population health insights from the data.
“From the beginning, our focus with the Healthy Nevada Project has been on delivering personalized health data to our communities that will ultimately drive positive change for our state,” said Anthony Slonim, M.D., DrPH, president and CEO of Renown Health, and president of Renown IHI. “We are very excited about the opportunities the next phase of this groundbreaking study will offer. Community participants will be able to gain deeper, actionable insights into their DNA data, while our research teams gain unprecedented access to the largest clinical DNA sequencing facility in the world.”
Northern Nevada’s healthcare catchment spans 100,000 square miles and serves almost 1 million people. The diverse population, generational healthcare data and innovative combination of leading-edge research tools and detailed environmental databases make the region an ideal location for advanced health science.
“Our pilot phase used genotyping, which was a great start, but moving to NGS sequencing and inviting an additional 40,000 people to participate will dramatically accelerate what we can learn about the human genome and has the potential to greatly improve preventative health,” said Joseph Grzymski, Ph.D., an associate research professor at DRI, co-director of Renown IHI, and principal investigator of the Healthy Nevada Project.
“Our mission is to empower every person to improve their life through DNA. We invested heavily in our Exome+ assay, partner infrastructure, and CLIA- and CAP-accredited laboratory – which is now the largest clinical exome sequencing facility in the world – with the vision of empowering individuals with access to data about themselves and the DNA-powered products that enable them to take a more active role in their health,” said Robin Thurston, CEO of Helix. “Helix is proud to support this important project which will empower people to make better health choices and will contribute to novel genomics discoveries.”
Community members are encouraged to stay tuned to HealthyNV.org as Renown IHI finalizes the details of phase two enrollment of the Healthy Nevada Project. Enrollment is expected to open this spring.
Renown Institute for Health Innovation is a collaboration between Renown Health - a locally governed and locally owned, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California; and the Desert Research Institute - a recognized world leader in investigating the effects of natural and human-induced environmental change and advancing technologies aimed at assessing a changing planet. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Learn more at www.healthynv.org.
Helix is a personal genomics company with a simple but powerful mission: to empower every person to improve their life through DNA. We’ve created the first marketplace for DNA-powered products where people can explore diverse and uniquely personalized products developed by high-quality partners. Helix handles sample collection, DNA sequencing, and secure data storage so that our partners can integrate DNA insights into products across a range of categories, including ancestry, entertainment, family, fitness, health and nutrition. From profound insights to just-for-fun discoveries, Helix is here to help people live a fuller life. Helix is headquartered in the San Francisco Bay Area, and has a CLIA- and CAP-accredited Next Generation Sequencing lab in San Diego powered by Illumina (NASDAQ:ILMN) NGS technology. Helix was created in 2015 with founding support from Illumina, its largest shareholder. Learn more at www.helix.com.
Desert Research Institute
Director of Communications and New Media